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Bolti ár: Internetes ár: |
Kiadó: B.C.Decker
2001
1-55009-137-9
As a result of improvements in sanitation and overall living conditions during the early part of the 20th century and the subsequent introduction of many vaccines and antibiotics, considerable complacency has developed regarding infectious diseases, which many regarded as either preventable by immunization or treatable by antibiotics. However, infectious diseases remain the leading cause of death worldwide. In the United States, infectious diseases are the third leading cause of death. The World Health Organization estimates that approximately 17 million (33%) of the 52 million deaths that occurred worldwide in 1997 were caused by microbial agents. In addition, the last 25 years have produced a series of reminders regarding the challenges that infectious diseases will continue to pose domestically and globally.
Experiences with these and other emerging and re emerging diseases should have alerted clinicians, microbiologists, researchers, public health officials, policy makers, and the public to the critical importance of ensuring the capacity to detect, respond to, and control these infections. The Institute of Medicine (IOM) published a report entitled "Emerging Infections: Microbial Threats to Health in the United States" in the fall of 1992. This report, developed under the leadership of Drs. Joshua Lederberg and Robert Shope, emphasized the global context of emerging infectious diseases, highlighted this complacency regarding emerging infections, and identified six important factors in disease emergence and re emergence. One of these factors was the dramatic increase in the frequency and speed of global travel and commerce. The others included changes in human demographics and behaviors, advances in technology and industry, economic development and changes in land use, microbial adaptation and change, and deterioration in the public health system at the local, state, national, and global levels. The IOM committee made 15 recommendations that stressed the need to improve surveillance and response capacity and identified research issues and training priorities.
A number of recent domestic challenges occurred in an international context, providing a reminder that we do indeed live in a "global village." For example, several foodbome outbreaks have been international in scope (e.g., Cyclospora gastroenteritis in the United States and Canada associated with raspberries imported from Guatemala), and drug resistance is well recognized as a global problem (e.g., the continued emergence and intercountry spread of penicillin resistance in Streptococcus pneumoniae and the recent identification of Staphylococcus aureus infections caused by strains with partial resistance to vancomycin in Japan, France, and the United States).
Internationally, a number of outbreaks have provided similar reminders. Examples include plague in India and Hendra. virus infection in Australia in 1994, Ebola hemorrhagic fever in Zaire and leptospirosis in Nicaragua in 1995, a new variant of CreutzfeldtJakob disease in the United Kingdom, a large outbreak of Escherichia coli 0157:H7 hemorrhagic colitis in Japan in 1996, avian influenza in Hong Kong in 1997, and amebiasis in Georgia in 1998. Each of these outbreaks illustrates the need for clinicians to be aware of emerging diseases in other countries, the critical importance of adequate surveillance and response capacity, the critical role of the diagnostic laboratory, and the global implications of local problems.
The ability to address these emerging and re emerging microbial threats requires adequate surveillance and response capacity, ongoing research programs, effective prevention and control programs, and strengthening of the public health system locally, at the state and national levels, and internationally. The challenges that these diseases will continue to pose demand a multidisciplinary approach and a supply of trained health professionals.
Clinicians involved in travel medicine are uniquely positioned both to recognize emerging infectious diseases acquired by travelers and to take action to prevent infectious diseases in travelers. These professionals are in a unique position to help bridge the gap between clinical medicine and public health. They need skills in both risk assessment and risk management. They need communication skills to advise the broad array of individuals who travel abroad for business, pleasure, education, and visits with family and friends. They must be skilled in the differential diagnoses of a broad array of syndromes. Finally, they must be alert to the possibility that one of their patients may be part of an epidemic abroad that may require public health action. This book, the scope of which has been expanded far beyond that of the first edition, should serve as a valuable source of information for them and their colleagues in related disciplines as they strive to prevent, diagnose, and treat the myriad of potential infectious and noninfectious diseases and conditions that travelers may experience as we enter the next millennium.